Alpha was born and raised in Olive Branch, Mississippi, a very rural town just south of the Tennessee state line. She graduated from the Central Mississippi College where she obtained a degree in Education. After college, she worked for the Shelby County School District as a teacher and with the Internal Revenue Service as an Examinations Agent before relocating to the San Francisco Bay Area with her family in 1977. Shortly thereafter, she started her own Income Tax business, preparing income taxes from the family home. In January 1987, she accepted a position with The City & County of San Francisco as a Juvenile Counselor at the Youth Guidance Center. She worked as a Juvenile Counselor for two years before being promoted to Deputy Probation Officer for the Adult Probation Department in the City and County of San Francisco.

Her most notable assignments with the Adult Probation Department have included a six year assignment as an Intensive Services Probation Officer, supervising mentally ill offenders; seven years as Lead Case Manager for the Network Treatment Grant For Women, a program that targeted women in the Criminal Justice System with substance abuse issues; and five years as Director of the P.O.W.E.R. Program (Probation Officers Working to End Recidivism).

Alpha is the founder and Chairperson of the Inner City Adolescent Network , Inc. (ICAN) in San Francisco County and the Peninsula Omega Youth Club (POYC) in San Mateo County. POYC is a 501(c) 3 Non Profit Corporation with a mission to kindle hope, bound with the reality of life, within the youth who have the least hope. Alpha is committed to and believes in helping underserved youth - who are either involved with the criminal justice system, surrounded by poverty, drugs, violence, mis-education, or other harmful influences - to reach their full potential.

Alpha Buie has received numerous awards and accolades for her work with at risk youth, including The Chief Probation Officer's Recognition of Excellence, California Probation & Parole Officers Association's Loren Beckley Award, California Legislature Assembly Certificate of Recognition and Certificate of Special Congressional Recognition from Congressman Tom Lantos, to name a few.

Alpha is a member of Alpha Kappa Alpha Sorority, Incorporated- Delta Zeta Omega Chapter in San Francisco, an associate member of the American Bar Association - Family Law Division, and a faithful member of Providence Baptist Church in San Francisco.

Alpha is a mother of two and grandmother of four.